一、基本信息

黎佳，博士，副教授，硕士生导师

电子邮件：lijia1983412(AT)163.com

研究领域：天然产物生物合成

二、教育背景

2005.09–2010.06  中国科学院武汉病毒研究所，理学博士

2001.09–2005.07  四川农业大学生命科学与理学院，获学学士

三、工作经历

2018.07至今          3344体育会员，副教授

2010.06–2018.07   中国科学院武汉植物园，任助理研究员、副研究员。

四、科研项目

1. 国家自然科学基金青年科学基金项目（31300258）：3'-甲氧基葛根素生物合成途径中关键甲基转移酶基因的克隆与功能分析，2014.01–2016.12，23万元，主持

2. 国家自然科学基金面上项目（31670300）：薯蓣皂素合成下游路径关键P450酶基因的分离与功能分析2017.01–2020.12，62万元，参与

3. 国家自然科学基金青年科学基金项目（31600240）：灵芝三萜酸下游合成路径CYP450s基因挖掘与功能分析，2017.01–2019.12，20万元，参与

4. 国家自然科学基金面上项目（31370339）：倍半萜药用化合物苍耳素生物合成关键P450基因的分离与功能分析，2014.01–2017.12，80万元，参与

5. 中国科学院知识创新工程重要方向项目子项目（Y12A214E03）：葛根素生物合成分子机理研究，2011.01–2013.12，35万元，参与

五、代表性论文（#共同第一作者，*通讯作者）

1. Li J, Liang Q, Li C, Liu M, Zhang Y*. (2018) Comparative transcriptome analysis identifies putative genes involved in dioscin biosynthesis in Dioscorea zingiberensis. Molecules 23, 454.

2. Li J, Shen J, Sun Z, Li J, Li C, Li X, Zhang Y*. (2017) Discovery of several novel targets that enhance β-carotene production in Saccharomyces cerevisiae. Frontiers in Microbiology 8, 1116.

3. Li J, Li C, Gou J, Wang X, Fan R, Zhang Y*. (2016). An alternative pathway for formononetin biosynthesis in Pueraria lobata. Frontiers in Plant Science 7, 861.

4. Li J, Li C, Gou J, Zhang Y*. (2016. Molecular cloning and functional characterization of a novel isoflavone 3'-O-methyltransferase from Pueraria lobata. Frontiers in Plant Science 7, 793.

5. Li J, Li Z, Li C, Gou J, Zhang Y*. (2014). Molecular cloning and characterization of an isoflavone 7-O-glucosyltransferase from Pueraria lobata. Plant Cell Reports 33, 1173–1185.

6. Li J, Yang L, Hu X, Zheng D, Yan J, Yuan Z*. (2013) Nanoscale mono- and multi-layer cylinder structures formed by recombinant S-layer proteins of mosquitocidal Bacillus sphaericus C3-41. Applied and Environmental Microbiology 97, 7275–7283.

7. Li J, Hu X, Yan J, Yuan Z*. (2009) Species-specific cell wall binding affinity of the S-layer proteins of mosquitocidal bacterium Bacillus sphaericus C3-41. Applied and Environmental Microbiology 75, 3891–3895.

8. Wang X, Li C, Zhou C, Li J, Zhang Y*. (2017) Molecular characterization of the C-glucosylation for puerarin biosynthesis in Pueraria lobata. The Plant J 90, 535–546.

9. Wang X, Fan R, Li J, Li C, Zhang Y*. (2016) Molecular cloning and functional characterization of a novel (iso)flavone 4',7-O-diglucoside glucosyltransferase from Pueraria lobata. Frontiers in Plant Science 7, 387.

10. Wang X, Li S, Li J, Li C, Zhang Y*. (2015) De novo transcriptome sequencing in Pueraria lobata to identify putative genes involved in isoflavones biosynthesis. Plant Cell Reports 34, 733–743.

11. Li Z, Li C, Li J, Zhang Y*. (2014) Molecular cloning and functional characterization of two divergent 4-coumarate, coenzyme A ligases from Kudzu (Pueraria lobata). Biological and Pharmaceutical Bulletin 37, 113–122.

12. Huang L, Li J, Ye H, Li C, Wang H, Liu B, Zhang Y*. (2012) Molecular characterization of the pentacyclic triterpenoid biosynthetic pathway in Catharanthus roseus. Planta 236, 1571–1581.

13. Hu X, Li J, Hansen BM, Yuan Z*. (2008) Phylogenetic analysis and heterologous expression of surface layer protein SlpC of Bacillus sphaericus C3-41. Bioscience, Biotechnology, and Biochemistry 72, 1257–1263.

14. 苟君波，李长福，陈方方，李兆波，黎佳*. 2013. 野葛异黄酮合酶基因的分离与功能验证. 植物科学学报. 31, 398–405.

15. 李晓华，李长福，黎佳，刘梦迪，章焰生*. 2017. 两种影响因子对葫芦巴发根转化率的影响. 植物科学学报. 35, 735–740.

六、专利

1. 章焰生，黄莉莉，李长福，黎佳。羽扇豆醇C28氧化酶基因及其获得方法与应用。专利号：ZL201110342944.3