一、基本信息
肖盼，博士，讲师
电子邮件：xiaopan@hubu.edu.cn
研究方向：化学生物学，生物催化
二、教育背景
2017.10-2021.04 诺曼底大学-法国鲁昂国立应用科学学院，化学，理学博士
2014.09-2017.07 中国科学院上海有机化学研究所，有机氟化学重点实验室，有机化学，理学硕士
2010.09-2014.06 湖北大学化学化工学院，化学生物学，学士
三、工作经历
2023.08至今 湖北大学，省部共建生物催化与酶工程国家重点实验室，讲师
2021.06-2023.07 国科大杭州高等研究院/中国科学院上海药物研究所联合培养，药物科学与技术学院，博士后
四、代表性论文（#共同第一作者）
1. Xiao P#, Duan Z#, Liu Z#, Chen L, Zhang D, Liu L, Zhou C, Gan J, Dong Z, Yang C-G, Rational Design of RNA Demethylase FTO Inhibitors with Enhanced Antileukemia Drug-Like Properties. J Med Chem 2023, 66 (14), 9731-9752.
2. Xiao P, Pannecoucke X, Bouillon J-P, Couve-Bonnaire S, Wonderful fusion of organofluorine chemistry and decarboxylation strategy. Chem Soc Rev 2021, 50 (10), 6094-6151.
3. Xiao P, Pannecoucke X, Bouillon J-P, Couve-Bonnaire S, Palladium-Catalysed Oxidative Decarboxylative Cross-Coupling of Heteroarenes with CF3-Acrylic Acids. ChemistrySelect 2021, 6 (29), 7367-7371.
4. Xiao P, Pannecoucke X, Bouillon J-P, Couve-Bonnaire S, Ligand Free Palladium-Catalyzed Synthesis of α-Trifluoromethylacrylic Acids and Related Acrylates by Three-Component Reaction. Adv Synth Catal 2020, 362 (4), 949-954.
5. Xiao P, Schlinquer C, Pannecoucke X, Couve-Bonnaire S, Bouillon J-P, Ligand-free palladium-catalyzed Mizoroki-Heck reaction to synthesize valuable α-trifluoromethylacrylates. J Fluorine Chem 2020, 233, 109483.
6. Xiao P, Schlinquer C, Pannecoucke X, Bouillon J-P, Couve-Bonnaire S, Synthesis of α-Trifluoromethylacrylates by Ligand-Free Palladium-Catalyzed Mizoroki-Heck Reaction. J Org Chem 2019, 84 (4), 2072-2082.
7. Xiao P, Ni C, Miao W, Zhou M, Hu J, Chen D, Hu J, Fluoroalkylation of Various Nucleophiles with Fluoroalkyl Sulfones through a Single Electron Transfer Process. J Org Chem 2019, 84 (13), 8345-8359.
8. Xiao P, Rong J, Ni C, Guo J, Li X, Chen D, Hu J, Radical (Phenylsulfonyl)difluoromethylation of Isocyanides with PhSO2CF2H under Transition-Metal-Free Conditions. Org Lett 2016, 18 (22), 5912-5915.
