毛伍祥

作者：系统管理员发布时间：2016-07-05 阅读次数:

一、基本信息

毛伍祥，博士，副教授、硕士研究生导师

电子邮件：wxmao(AT)hubu.edu.cn

研究领域：核酸生物学、表观遗传学

二、教育背景

2010.09–2015.06 武汉大学化学生物学，理学博士

2005.09–2009.06 湖北大学化学生物学，理学学士（国家理科基地班）

三、工作经历

2018.07至今 3344体育会员，副教授

2016.03–2018.06 3344体育会员，讲师

2018.09–2019.09 美国Scripps研究所，访问学者

四、科研项目

1. 国家自然科学基金（21708006）：基于生物正交反应的DNA脱碱基位点荧光探针的构建及其在细胞成像和寻找肿瘤标志物中的应用研究，2018/01–2020/12，主持

2. 湖北大学自然科学基金：“荧光增强型”DNA脱碱基位点探针的设计、合成与应用，2017/01–2018/12，主持

五、代表著作（^#共同第一作者，*通讯作者）

1. Mao W, Xu X, He H, Huang R, Chen X, Xiao H, Yu Z, Liu Y, Zhou X. (2015) Specific recognition of guanines in non-duplex regions of nucleic acids with potassium tungstate and hydrogen peroxide. Nucleic Acid Research 43, e3.

2. Wang Y, Liu C, Wang T, Hong Y, Yuan Y, Yu S, Su H, Song H, Peng S, Liu S, Zhou X, Rong H, Mao W*, Zhou X*. (2016) Highly selective detection of 5-methylcytosine in genomic DNA based on asymmetric PCR and specific DNA damage reagents. Analytical Chemistry 88, 3348–3353.

3. Wu F, Liu C, hen Y, Yang S, Xu J, Huang R, Wang X, Li M, Liu W, Mao W*, Zhou X*. (2016) Visualization of G-quadruplexes in gel and in live cells by a near-infrared fluorescent probe. Sensors and Actuators B: Chemical 236, 268–275.

4. Mao W, Hu J, Hong T, Xing X, Wang S, Chen X, Zhou X*. (2013) A convenient method for selective detection of 5-hydroxymethylcytosine and 5-formylcytosine sites in DNA sequences. Organic Biomolecular chemistry 11, 3568–3572.

5. Han J, Chu C, Cao G, Mao W*, Wang S, Zhao Z, Gao M, Ye H*, Xu X*. (2018) A simple boronic acid–based fluorescent probe for selective detection of hydrogen peroxide in solutions and living cells. Bioorganic Chemistry 81, 362–366.

6. Yu X^#, Mao W^#, Zhai Y, Tong C, Liu M, Ma L, Yu X*, Li S*. (2017) Anti-tumor activity of metformin: from metabolic and epigenetic perspectives. Oncotarget 8, 5619–5628.

7. Xu X, Mao W^#, Lin F, Hu J, He Z, Weng X, Wang C, Zhou X*. (2016) Enantioselective Diels–Alder reactions using a G-triplex DNA-based catalyst. Catalysis Communications 74, 16–18.

六、专利